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Hyperventilation following head injury |
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February 2007
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Hyperventilation following head injury: effect on ischemic burden and cerebral oxidative metabolism. Coles JP et al. Crit Care Med. 2007 Feb;35(2):568-78. PubMed
More evidence that hyperventilation of head injury victims potentially increases neuronal injury.
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Magnesium sulfate for head injury |
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January 2007
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Pilot study to determine the hemodynamic safety and feasibility of magnesium sulfate infusion in children with severe traumatic brain injury.
Natale, JoAnne E. MD et al. Pediatric Critical Care Medicine. 8(1):1-9, January 2007.
Pubmed
Demonstrates the difficulty of performing studies in this patient group, resulting in a small study from which it is difficult to draw conclusions.
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Corticosteroids for Sepsis |
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Historical
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Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis. Annane D et al. BMJ. 2004 Aug 28;329(7464):480. Pubmed.
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The SAFE study |
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Historical
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A Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit. SAFE Study Investigators. NEJM 2004;350:2247-2256. Pubmed
No significant differences between 0.9% saline and 4% albumin for resuscitation of adults in ICU...
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How to read a paper... |
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Historical
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In 1997 the BMJ published a series of papers by Trisha GreenHalgh entitled 'How to read a paper'. These provide a good introduction to objective analysis of research papers.
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